Health and Fitness What are the effects of a sedentary lifestyle on muscle and bone strength? February 4, 2026 by Riding A sedentary lifestyle, characterized by prolonged periods of sitting or inactivity, can negatively impact both muscle and bone strength. Lack of physical activity reduces the mechanical stimulus necessary for bone formation and maintenance, leading to decreased bone density and increased risk of fractures. Similarly, muscles weaken and atrophy from disuse, reducing overall strength and endurance. […] Read more »